Hyderabad to lead production of India’s first indigenous malaria vaccine

A decade-long effort to develop India’s first indigenous malaria vaccine could soon bear fruit, with a significant part of the work taking place in Hyderabad.

In a major development, two Hyderabad-based vaccine manufacturers, Indian Immunologicals Limited (IIL) and Biological E Limited, have received a licence from the Indian Council of Medical Research (ICMR) to manufacture the country’s



first indigenous malaria vaccine.

Named AdFalci Vax, the vaccine is India’s first indigenous, multi-stage recombinant malaria vaccine. Unlike conventional vaccines, it has been designed to attack the malaria parasite Plasmodium falciparum at multiple stages of its life cycle, before it enters the liver and later in the bloodstream, making it more effective in stopping the infection from spreading.